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- Jennifer H Tomlinson, Saif Ullah, Poul Erik Hansen, Michael P Williamson
- Journal of the American Chemical Society
- 2009
NMR investigations have been carried out on the B1 domain of protein G. This protein has six lysine residues, of which three are consistently found to form surface-exposed salt bridges in crystal… (More)
- Jennifer H Tomlinson, Victoria L Green, Patrick J Baker, Michael P Williamson
- Proteins
- 2010
We report chemical shifts for H(N), N, and C' nuclei in the His-tagged B1 domain of protein G (GB1) over a range of pH values from pH 2.0 to 9.0, which fit well to standard pH-dependent equations. We… (More)
- Jennifer H Tomlinson, C. Jeremy Craven, Michael P Williamson, Maya J Pandya
- Proteins
- 2010
A number of signals in the NMR spectrum of the B1 domain of staphylococcal protein G (GB1) show a chemical shift dependence on the concentration of the protein at pH 3 but not at neutral pH, implying… (More)
- Arya Tanmay Gupta, Carmine G. Monteferrante, +7 authors Alex J O'Neill
- Antimicrobial agents and chemotherapy
- 2016
GSK2251052 is a broad-spectrum antibacterial inhibitor of leucyl tRNA-synthetase (LeuRS) that has been evaluated in phase II clinical trials. Here, we report the identification of a clinical isolate… (More)
- Jennifer H Tomlinson, Michael P Williamson
- Journal of biomolecular NMR
- 2012
Temperature coefficients have been measured for backbone amide (1)H and (15)N nuclei in the B1 domain of protein G (GB1), using temperatures in the range 283-313 K, and pH values from 2.0 to 9.0.… (More)
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