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Self-concept clarity (SCC) references a structural aspect oftbe self-concept: the extent to which self-beliefs are clearly and confidently defined, internally consistent, and stable. This article reports the SCC Scale and examines (a) its correlations with self-esteem (SE), the Big Five dimensions, and self-focused attention (Study l); (b) its criterion(More)
Self-esteem has become a household word. Teachers, parents, therapists, and others have focused efforts on boosting self-esteem, on the assumption that high self-esteem will cause many positive outcomes and benefits-an assumption that is critically evaluated in this review. Appraisal of the effects of self-esteem is complicated by several factors. Because(More)
This article examines the association between evaluative and knowledge components of the self. Four studies tested the hypothesis that the self-concepts of low-self-esteem (LSE) people are characterized by less clarity or certainty than those of high-self-esteem (HSE) people. LSE Ss exhibited less extremity and self-reported confidence when rating(More)
Numerous longevity genes have been discovered in model organisms and altering their function results in prolonged lifespan. In mammals, some have speculated that any health benefits derived from manipulating these same pathways might be offset by increased cancer risk on account of their propensity to boost cell survival. The Sir2/SIRT1 family of(More)
The Human Phenotype Ontology (HPO) project, available at http://www.human-phenotype-ontology.org, provides a structured, comprehensive and well-defined set of 10,088 classes (terms) describing human phenotypic abnormalities and 13,326 subclass relations between the HPO classes. In addition we have developed logical definitions for 46% of all HPO classes(More)
Two studies examined the notion that negative affectivity (Watson & Clark, 1984) is associated with more accurate perceptions of conveyed impressions in social interactions. In Study 1 (n = 160), low self-esteem (LSE) and high self-esteem (HSE) subjects were paired with either an LSE or an HSE partner. After a 15-min interaction, they rated themselves,(More)
The present study is the first behavioral genetic investigation of relationships between the Dark Triad of personality--Machiavellianism, narcissism, and subclinical psychopathy--and moral development. Participants were 154 monozygotic twin pairs and 82 same-sex dizygotic twin pairs. Higher scores on Machiavellianism and psychopathy were positively(More)
1. PROPOSAL Students in science and engineering are poorly served by most general-purpose CS-1 courses, which rarely discuss scientific problems or applications. At the same time, fewer and fewer computer science students are exposed to scientific ideas or thinking in any of their introductory courses. This divide hurts both sides: scientists and engineers(More)
Adenocarcinoma of the lung is the leading cause of cancer death worldwide. Here we report molecular profiling of 230 resected lung adenocarcinomas using messenger RNA, microRNA and DNA sequencing integrated with copy number, methylation and proteomic analyses. High rates of somatic mutation were seen (mean 8.9 mutations per megabase). Eighteen genes were(More)