Jennifer Blades

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Delta-like ligand 4 (Dll4) is a Notch ligand that is predominantly expressed in the endothelium. Evidence from xenografts suggests that inhibiting Dll4 may overcome resistance to antivascular endothelial growth factor therapy. The aims of this study were to characterize the expression of Dll4 in breast cancer and assess whether it is associated with(More)
We present HST/GHRS echelle observations of multiple interstellar lines of C I, Mg I, Cr II, and Zn II towards both stars in the µ Cru binary system. Despite large differences in the profiles of the neutral species, no significant variations between the stars are seen in the Cr II and Zn II line profiles. In particular, the Zn II absorption observed at-8.6(More)
We have obtained spectra of three QSO/AGNs with the GHRS aboard the Hubble Space Telescope to search for absorption from low column density gas in the halo of the dwarf spheroidal (dSph) galaxy Leo I. The probe sightlines pass 2.1, 3.7, and 8.1 kpc from the center of the galaxy, but no C IV, Si II, or Si IV absorption is found at the velocity of Leo I. The(More)
To expand the known number of low-redshift galaxies which lie close to bright (V < 17.2) QSO lines of sight, we have identified 24 galaxies within 11 arcmins of nine QSOs which have been observed with the Hubble Space Telescope (HST). Galaxies are found between redshifts of 0.0114− 0.145 and lie between 39− 749 h kpc from QSO sightlines. Knowing the(More)
The morphology of planetary nebulae (PNe) provides an essential tool for understanding their origin and evolution, as it reflects both the dynamics of the gas ejected during the TP–AGB phase, and the central star energetics. Here we study the morphology of 27 Magellanic Cloud planetary nebulae (MCPNe) and present an analysis of their physical(More)
We have obtained spectra of three QSO/AGNs with the GHRS aboard the Hubble Space Telescope to search for absorption from low column density gas in the halo of the dwarf spheroidal (dSph) galaxy Leo I. The probe sightlines pass 2.1, 3.7, and 8.1 kpc from the center of the galaxy, but no C IV, Si II, or Si IV absorption is found at the velocity of Leo I. The(More)
We have obtained spectra of three QSO/AGNs with the GHRS aboard the Hubble Space Telescope to search for absorption from low column density gas in the halo of the dwarf spheroidal (dSph) galaxy Leo I. The probe sightlines pass 2.1, 3.7, and 8.1 kpc from the center of the galaxy, but no C IV, Si II, or Si IV absorption is found at the velocity of Leo I. We(More)