Jennie C Brand-Miller

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BACKGROUND Inconsistent findings from observational studies have prolonged the controversy over the effects of dietary glycemic index (GI) and glycemic load (GL) on the risk of certain chronic diseases. OBJECTIVE The objective was to evaluate the association between GI, GL, and chronic disease risk with the use of meta-analysis techniques. DESIGN A(More)
OBJECTIVE To systematically tabulate published and unpublished sources of reliable glycemic index (GI) values. RESEARCH DESIGN AND METHODS A literature search identified 205 articles published between 1981 and 2007. Unpublished data were also included where the data quality could be verified. The data were separated into two lists: the first representing(More)
BACKGROUND In westernized societies, acne vulgaris is a nearly universal skin disease afflicting 79% to 95% of the adolescent population. In men and women older than 25 years, 40% to 54% have some degree of facial acne, and clinical facial acne persists into middle age in 12% of women and 3% of men. Epidemiological evidence suggests that acne incidence(More)
OBJECTIVE The use of diets with low glycemic index (GI) in the management of diabetes is controversial, with contrasting recommendations around the world. We performed a meta-analysis of randomized controlled trials to determine whether low-GI diets, compared with conventional or high-GI diets, improved overall glycemic control in individuals with diabetes,(More)
BACKGROUND Despite the popularity of low-glycemic index (GI) and high-protein diets, to our knowledge no randomized, controlled trials have systematically compared their relative effects on weight loss and cardiovascular risk. METHODS A total of 129 overweight or obese young adults (body mass index, > or =25 [calculated as weight in kilograms divided by(More)
BACKGROUND Pregnancy is a condition in which the glycemic index (GI) may be of particular relevance because maternal glucose is the main energy substrate for intrauterine growth. OBJECTIVE The aim was to compare the effects of low-GI and conventional dietary strategies on pregnancy outcomes in healthy women. Compliance and acceptability were also(More)
BACKGROUND Sialic acid, a key component of both human milk oligosaccharides and neural tissues, may be a conditional nutrient during periods of rapid brain growth. OBJECTIVE We tested the hypothesis that variations in the sialic acid content of a formula milk would influence early learning behavior and gene expression of enzymes involved in sialic acid(More)
The role of glycemic index (GI) in the prevention of diabetes remains controversial. Some, but not all, prospective cohort studies have yielded positive relationships (1–8). A significant limitation of studies to date has been the fact that the food frequency questionnaires (FFQs) used were not validated for their ability to accurately assess GI. The(More)
BACKGROUND Growth in normal and malignant tissues has been linked to hyperinsulinemia and insulin-like growth factors (IGFs). We hypothesized that IGF and IGF-binding protein (IGFBP) responses may be acutely affected by differences in the glycemic index (GI) of foods. OBJECTIVE We compared the postprandial responses of IGFs and IGFBP to 2 foods of similar(More)
Weight loss can be achieved by any means of energy restriction, but the challenge is to achieve sustainable weight loss and prevent weight "creep" without increasing the risk of chronic disease. The modest success of low fat diets has prompted research on alternative dietary strategies, including high protein diets and low glycemic index (GI) diets.(More)