Jenna Jacobson

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BACKGROUND Breast-conservation therapy for early-stage breast cancer is now an accepted treatment, but there is still controversy about its comparability with mastectomy. Between 1979 and 1987, the National Cancer Institute conducted a randomized, single-institution trial comparing lumpectomy, axillary dissection, and radiation with mastectomy and axillary(More)
PURPOSE The records of 28 patients with sarcomas of the hand and foot treated at the National Cancer Institute (NCI) between 1977 and 1992 were reviewed to assess local control and functional results. METHODS AND MATERIALS Histologic types included 15 cases of the Ewing's sarcoma family of tumors, 7 cases of alveolar rhabdomyosarcoma, and 6 cases of(More)
BACKGROUND This study was conducted to determine the feasibility of, and improve outcome by, incorporating ifosfamide and etoposide (IE) into the therapy of newly diagnosed patients with Ewing's sarcoma family of tumors of bone and soft tissue. METHODS Fifty-four newly diagnosed patients received 7 cycles of vincristine, doxorubicin, and cyclophosphamide(More)
BACKGROUND Stage IIIA,B breast cancer is commonly treated with neoadjuvant chemotherapy because of high objective response rates and improved operability. Criteria for subsequent selection of local therapy--mastectomy, radiotherapy, or both--are not well defined. We adopted a policy of selective local therapy based on rebiopsy of the breast and clinical(More)
PURPOSE To evaluate whether recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) reduces the hematologic toxicities and supportive care requirements of an intensive combination chemoradiotherapy regimen in pediatric and young adult sarcoma patients. PATIENTS AND METHODS Thirty-seven newly diagnosed patients age 1 to 25 years were(More)
We conducted a prospective randomized trial to evaluate the ability of the interleukin-3/granulocyte-macrophage colony-stimulating factor (GM-CSF) fusion protein, PIXY321, to ameliorate cumulative thrombocytopenia after multiple cycles of 5-fluorouracil, leucovorin, doxorubicin, cyclophosphamide (FLAC) chemotherapy compared with GM-CSF in patients with(More)
The Social Media & Society Conference is an annual international gathering of leading social media researchers from around the world. Now, in its sixth year, the 2015 conference is being held in Toronto, Canada, on July 27-29. The conference's intensive three-day program provides 18 full papers, 78 work-in-progress papers, 5 panels, and 52 posters. The(More)
This paper is the Introduction to the 2016 Proceedings of the International Conference on Social Media and Society, an annual gathering of leading social media researchers from around the world. Now, in its 7th year, the 2016 conference is hosted at Goldsmiths, University of London, UK from July 11 to 13. The conference's intensive three-day program(More)
Cumulative thrombocytopenia is a dose-limiting toxicity of dose-intensive chemotherapy for advanced breast cancer. In this phase I study, we have studied the hematologic toxicity associated with sequential interleukin-3 (IL-3) and granulocyte-macrophage colony-stimulating factor (GM-CSF; molgramostim) administration after multiple cycles of FLAC(More)