Jen-Chih Lin

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PURPOSE DNA BER pathway is related with carcinogenesis. We hypothesized that functional polymorphisms of three BER genes, XRCC1, apurinic/apyrimidinic endonuclease (APE1), and ADPRT, confer risks for DTC and its progression. EXPERIMENTAL DESIGN Five common nonsynonymous single nucleotide polymorphisms (Arg194Trp, Arg280His, and Arg399Gln for XRCC1;(More)
BACKGROUND The aim of this present study is to define the significance of recurrent laryngeal nerve palsy (RLNP) detected before surgery for thyroid diseases with regard to the incidence of malignancy, histopathologic distribution, extrathyroidal invasion, management, and prognosis. METHODS Six hundred and twenty-two patients underwent operation for(More)
The purpose of this study was to review the safety of total thyroidectomies for benign thyroid disease, with special emphasis on the comparison between Graves' disease and non-Graves' disease. In this study, 107 patients who underwent total thyroidectomies for clinically benign thyroid disease performed by the same surgeon between January 1987 and December(More)
BACKGROUND The antioxidant enzyme glutathione peroxidase 3 (GPX3) can lessen the oxidative stress in the thyroid gland. We tested for the association between tagging single nucleotide polymorphisms (tSNPs) of the GPX3 gene and the risk of differentiated thyroid cancer (DTC). METHODS A total of 6 tSNPs (rs3763013, rs8177412, rs3805435, rs3828599,(More)
OBJECTIVES To analyze mastoid findings, such as facial nerve dehiscence (FND), labyrinthine fistula, and dural exposure; to review its incidence at cholesteatoma surgery; to analyze its association with semicircular canal fistula; and to elucidate its relationship with dural exposure. DESIGN One hundred fifty-two patients (65 males and 87 females; 155(More)
OBJECTIVE To identify the incidence of dehiscence of the facial nerve in patients undergoing surgery for cholesteatoma and to describe its relevance with iatrogenic facial nerve injury. STUDY DESIGN AND SETTING This was a retrospective study including 117 tympanoplasties with or without mastoidectomy performed in 49 men and 66 women. RESULTS The(More)
The supercube is a generalization of interconnection network that is derived from the hypercube. Unlike the hypercube, the supercube can be constructed for any number of nodes. That is, the supercube is incrementally expandable. In addition, the supercube retains the connectivity and diameter properties of the corresponding hypercube. In this paper, the(More)
The incrementally extensible hypercube (IEH) graph is a generalization of binary hypercube networks in that the number of nodes can be arbitrary in contrast to a strict power of 2. In this paper, the authors present an efficient model to fulfill the embedding of a full binary tree into a full IEH graph. As the model the authors proposed, an algorithm is(More)