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OBJECTIVE To investigate brain asymmetries of the auditory evoked potential (AEP) N100, T-complex, and P200 in response to monaural stimulation. METHODS Electroencephalographic (EEG) recordings from 68 channels were used to record auditory cortex responses to monaural stimulation from normal hearing participants (N=16). White-noise stimuli and 1000Hz(More)
Little is known about how the auditory cortex adapts to artificial input as provided by a cochlear implant (CI). We report the case of a 71-year-old profoundly deaf man, who has successfully used a unilateral CI for 4 years. Independent component analysis (ICA) of 61-channel EEG recordings could separate CI-related artifacts from auditory-evoked potentials(More)
Conductive hearing loss, produced by otitis media with effusion, is widespread in young children. However, little is known about its short- or long-term effects on hearing or the brain. To study the consequences of a conductive loss for the perception and processing of sounds, we plugged the left ear canal of ferrets for 7-15 months during either infancy or(More)
Free-field detection by normal and monaural ferrets of a 500-Hz tone presented over 1 laterally placed loudspeaker and partially masked by narrow-band noise from 2 sources was studied at 2 angular separations of the noise sources (0 degree and 180 degrees). Monaural listening was achieved either by plugging 1 ear canal or removing 1 cochlea. Normal ferrets(More)
Electrical artifacts caused by the cochlear implant (CI) contaminate electroencephalographic (EEG) recordings from implanted individuals and corrupt auditory evoked potentials (AEPs). Independent component analysis (ICA) is efficient in attenuating the electrical CI artifact and AEPs can be successfully reconstructed. However the manual selection of CI(More)
The development of the ferret auditory system was examined using the auditory brainstem response (ABR). Longitudinal recordings were obtained under short-acting anaesthesia from individual animals at 4-h or 24-h intervals. Particular attention was focused on the period from postnatal day (P) 26 to P32 when the ferret auditory system becomes functional. ABR(More)
Auditory evoked potential (AEP) recordings often require subjects to ignore the stimuli and stay awake. In the present experiment, early (ABR), middle (MLR), and late latency (LLR) AEPs were recorded to compare the effect of five different distracting tasks: (1) doing nothing eyes open, (2) reading, (3) watching a movie, (4) solving a three-digit sum, and(More)
OBJECTIVE To investigate the long-term cortical changes in auditory evoked potential (AEP) asymmetries associated with profound unilateral deafness. METHODS Electroencephalographic (EEG) recordings from 68 channels were used to measure auditory cortex responses to monaural stimulation from 7 unilaterally deaf patients and 7 audiogram-matched controls.(More)
OBJECTIVES The objective of this study was to examine whether temporal non-linearities of the cochlear amplifier, as reflected by otoacoustic emissions (OAEs), exist and are distinct from any recording system non-linearities. METHODS Maximum length sequence stimulation, at various stimulus rates, was used to evoke OAEs from normally hearing subjects.(More)
Presenting clicks according to maximum length sequences (MLS) enables transient evoked otoacoustic emissions (TEOAE) to be recorded at very high stimulation rates. As the click rate is increased from 40 clicks/s up to a maximum rate of 5000 clicks/s there is a reduction in TEOAE amplitude that reaches an approximate asymptote at 1500 clicks/s. One(More)