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Mutations in casein kinase Iδ that are associated with migraine in patients cause changes in enzymatic function, pain behavior, cortical excitability, and astrocyte signaling in mice. The Pain of… Continue Reading
Spreading depolarizations are implicated in a diverse set of neurologic diseases. They are unusual forms of nervous system activity in that they propagate very slowly and approximately… Continue Reading
BACKGROUND AND PURPOSE Migraine is an extraordinarily common brain disorder for which treatment options continue to be limited. Agonists that activate the δ-opioid receptor may be promising for the… Continue Reading
Background and aims Precommitment refers to the ability to prospectively restrict the access to temptations. This study examined whether risk-taking during gambling is decreased when an individual… Continue Reading
s/presentations: Hoffmann J, Park JW, Storer RJ, Goadsby PJ. Magnesium and memantine do not inhibit nociceptive neuronal activity in the trigeminocervical complex of the rat. Journal of Headache and… Continue Reading