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Combination with antimicrobial peptide lyses improves loop-mediated isothermal amplification based method for Chlamydia trachomatis detection directly in urine sample
BackgroundChlamydia trachomatis is an obligate intracellular human pathogen and is the most common cause of sexually transmitted diseases affecting both men and women. The pathogen can causeExpand
The effect of main urine inhibitors on the activity of different DNA polymerases in loop-mediated isothermal amplification
ABSTRACT Background: The use of rapid amplification methods to detect pathogens in biological samples is mainly limited by the amount of pathogens present in the sample and the presence of inhibitingExpand
Implementation of antimicrobial peptides for sample preparation prior to nucleic acid amplification in point-of-care settings
ABSTRACT Background: A variety of sample preparation techniques are used prior to nucleic acid amplification. However, their efficiency is not always sufficient and nucleic acid purification remainsExpand