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Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression.

• Jeffrey W. Ryder, Carla P Portocarrero, +9 authors Karen L. Houseknecht
• Diabetes
• 2001

Conjugated linoleic acid (CLA) isomers have a number of beneficial health effects, as shown in biomedical studies with animal models. Previously, we reported that a mixture of CLA isomers improved… (More)

Myosin light chain kinase and myosin phosphorylation effect frequency-dependent potentiation of skeletal muscle contraction.

• Gang Zhi, Jeffrey W. Ryder, +5 authors James T Stull
• Proceedings of the National Academy of Sciences…
• 2005

Repetitive stimulation potentiates contractile tension of fast-twitch skeletal muscle. We examined the role of myosin regulatory light chain (RLC) phosphorylation in this physiological response by… (More)

Effect of contraction on mitogen-activated protein kinase signal transduction in skeletal muscle. Involvement Of the mitogen- and stress-activated protein kinase 1.

• Jeffrey W. Ryder, Richard Peter Fahlman, H Wallberg-henriksson, Dario R Alessi, Anna Krook, Juleen R Zierath
• The Journal of biological chemistry
• 2000

Growing evidence suggests that activation of mitogen-activated protein kinase (MAPK) signal transduction mediates changes in muscle gene expression in response to exercise. Nevertheless, little is… (More)

Postexercise glucose uptake and glycogen synthesis in skeletal muscle from GLUT4-deficient mice.

• Jeffrey W. Ryder, Yuichi Kawano, +4 authors Juleen R Zierath
• FASEB journal : official publication of the…
• 1999

To determine the role of GLUT4 on postexercise glucose transport and glycogen resynthesis in skeletal muscle, GLUT4-deficient and wild-type mice were studied after a 3 h swim exercise. In wild-type… (More)

Insulin- and glucose-induced phosphorylation of the Na(+),K(+)-adenosine triphosphatase alpha-subunits in rat skeletal muscle.

• Alexander V Chibalin, Marina V. Kovalenko, Jeffrey W. Ryder, Eric Feraille, H Wallberg-henriksson, Juleen R Zierath
• Endocrinology
• 2001

Phosphorylation of the alpha-subunits of Na(+),K(+)-adenosine triphosphatase in response to insulin, high extracellular glucose concentration, and phorbol 12-myristate 13-acetate was investigated in… (More)

Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: differential effects on insulin-receptor substrates 1 and 2.

• Alexander V Chibalin, Min Yu, +5 authors Juleen R Zierath
• Proceedings of the National Academy of Sciences…
• 2000

Level of physical activity is linked to improved glucose homeostasis. We determined whether exercise alters the expression and/or activity of proteins involved in insulin-signal transduction in… (More)

Muscle fiber type specificity in insulin signal transduction.

• Xiao Mei Song, Jeffrey W. Ryder, Yuichi Kawano, Alexander V Chibalin, Anna Krook, Juleen R Zierath
• The American journal of physiology
• 1999

We determined the muscle fiber type-specific response of intracellular signaling proteins to insulin. Epitrochlearis (Epi; 15% type I, 20% type IIa, and 65% type IIb), soleus (84, 16, and 0%), and… (More)

Enhanced skeletal muscle contraction with myosin light chain phosphorylation by a calmodulin-sensing kinase.

• Jeffrey W. Ryder, Kim S. Lau, Kristine E. Kamm, James T Stull
• The Journal of biological chemistry
• 2007

Repetitive low frequency stimulation results in potentiation of twitch force development in fast-twitch skeletal muscle due to myosin regulatory light chain (RLC) phosphorylation by Ca(2+)/calmodulin… (More)

Signaling processes for initiating smooth muscle contraction upon neural stimulation.

• Hai-Lei Ding, Jeffrey W. Ryder, James T Stull, Kristine E. Kamm
• The Journal of biological chemistry
• 2009

Relationships among biochemical signaling processes involved in Ca2+/calmodulin (CaM)-dependent phosphorylation of smooth muscle myosin regulatory light chain (RLC) by myosin light chain kinase… (More)

Use of a novel impermeable biotinylated photolabeling reagent to assess insulin- and hypoxia-stimulated cell surface GLUT4 content in skeletal muscle from type 2 diabetic patients.

• Jeffrey W. Ryder, Jing Yang, +8 authors Geoffrey David Holman
• Diabetes
• 2000

Cell surface GLUT4 levels in skeletal muscle from nine type 2 diabetic subjects and nine healthy control subjects have been assessed by a new technique that involves the use of a biotinylated… (More)

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