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OBJECTIVE To compare fixed-flexion radiography of the knee with fluoroscopic semi-flexed radiography in terms of the reproducibility of measurements of minimum joint-space width (JSW) in the medial femorotibial joint. METHODS Posteroanterior radiographs of the right knees of 18 normal volunteers were acquired with the patients standing on an upright(More)
OBJECTIVE Minimum radiographic joint space width (mJSW) represents the Food and Drug Administration (FDA) standard for demonstrating structural therapeutic benefits for knee osteoarthritis (KOA), but only shows moderate responsiveness (sensitivity to change). We directly compare the responsiveness of magnetic resonance imaging (MRI)-based cartilage(More)
OBJECTIVE It has been shown that trabecular bone structure parameters extracted from radiographs known as fractal signature analysis (FSA) are able to predict structural outcomes such as radiographic osteoarthritis (OA) progression. Little is known about their involvement in early disease or about differences between subjects exposed to increased joint(More)
The progression of osteoarthritis (OA) can be monitored by measuring the minimum joint space width (mJSW) between the edges of the femoral condyle and the tibial plateau on radiographs of the knee. This is generally performed by a trained physician using a graduated magnifying lens and is prone to the subjectivity and variation associated with observer(More)
OBJECTIVE To compare the diagnostic performance of a computer-based method for measuring joint space width with the Sharp joint space narrowing (JSN) scoring method in patients with rheumatoid arthritis (RA). METHODS A random sample of patients with early RA, for whom sequential hand radiographs and Sharp scores were available, was selected from the(More)
The two principal forms of hand arthritis, rheumatoid arthritis (RA) and osteoarthritis (OA) have large clinical and economic costs. Radiography has been shown to be a useful tool to assess the condition of the disease. A hand radiograph, however, is a two-dimensional projection of a three-dimensional object. In this report we present the results of a study(More)
OBJECTIVE To compare intra- and inter-observer variation for measurements of wrist deformity using a manual method of measurement and a semi-automated digital system developed in our department. DESIGN Four observers measured radial angle, radial shift, radial length, palmar tilt, and dorsal shift on ten wrist-fracture films using a standardised protocol.(More)
Total knee arthroplasty is now a widely accepted treatment for late-stage arthritis. Wear of the polyethylene layer in prosthetic knees is a known cause of implant failure. Early detection of wear may allow prediction of device failure. In this paper we describe a fully automated image processing algorithm to measure the minimum tibiofemoral joint space(More)
Radiographic joint-space narrowing (JSN) is the principle indicator of cartilage loss in osteoarthritis (OA). JSN is usually assessed qualitatively by visual inspection or in clinical research, is measured manually with a graduated handheld lens directly applied to the x-ray film, or from digitized radiographs by hand tracing the joint margins with a mouse.(More)
Arthritis diseases are widespread with enormous societal costs. The two most common forms, rheumatoid arthritis and osteoarthritis, affect joints of the hand and cause narrowing of the joint spaces as the disease destroys the articular cartilage. Radiographic assessment is one of the most promising tools to detect subtle changes in joint space width (JSW),(More)