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  • Andrea James, Chanjae Lee, Andre M Williams, Krista Marie Angileri, Kira L. Lathrop, Jeffrey M Gross
  • Medicine, Biology
  • Developmental biology
  • 2016 (First Publication: 15 November 2016)
  • A critical aspect of vertebrate eye development is closure of the choroid fissure (CF). Defects in CF closure result in colobomas, which are a significant cause of childhood blindness worldwide.Expand
  • Richard J. Nuckels, Anthony Ng, Tristan Darland, Jeffrey M Gross
  • Medicine, Biology
  • Investigative ophthalmology & visual science
  • 2009 (First Publication: 1 February 2009)
  • PURPOSE The vacuolar (v)-ATPase complex is a key regulator of the acidification of endosomes, lysosomes, and the luminal compartments of several cell types, tissues, and organs; however, little isExpand
  • J. Brown, Sunit Dutta, +11 authors B. Brooks
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences
  • 2009 (First Publication: 3 February 2009)
  • The gene networks underlying closure of the optic fissure during vertebrate eye development are poorly understood. Here, we profile global gene expression during optic fissure closure using laserExpand
  • Jiwoon Lee, Jason R. Willer, Gregory B. Willer, Kierann E. Smith, Ronald G Gregg, Jeffrey M Gross
  • Medicine, Biology
  • Developmental biology
  • 2008 (First Publication: 1 July 2008)
  • In this study, we have characterized the ocular defects in the recessive zebrafish mutant blowout that presents with a variably penetrant coloboma phenotype. blowout mutants develop unilateral orExpand