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In this paper, we describe our initial implementation of the KAoS policy and domain services. While initially oriented to the dynamic and complex requirements of software agent applications, the services are also being adapted to general-purpose grid computing and web services environments as well. The KAoS services rely on a DAML description-logic-based(More)
Consider the following six systems-related terms. Sociotechnical systems emerged from research at the Tavistock Institute in the 1950s on the effects of the introduction of powered machines on the work, management-labor relations, and the lives, families, and societies of coal miners. 2 Human-machine systems is the idea, originating in industrial psychology(More)
Web Services power through explicit representations of Web resources underlying semantics and the development of an intelligent Web infrastructure that can fully exploit them. Semantic Web languages, such as OWL, extend RDF to let users specify ontologies comprising taxonomies of classes and inference rules. Both people and software agents can effectively(More)
The strength of hippocampal synapses can be persistently increased by signals that activate Ca2+/calmodulin-dependent protein kinase II (CaMKII). This CaMKII-dependent long-term potentiation is important for hippocampal learning and memory. In this work we show that CaMKII exhibits an intriguing switch-like activation that likely is important for changes in(More)
To increase the assurance with which agents can be deployed in operational settings, we have been developing the KAoS policy and domain services. In conjunction with Nomads strong mobility and safe execution features, KAoS services and tools allow for the specification, management, conflict resolution, and enforcement of DAML-based policies within the(More)
The availability of purified human recombinant interleukin 2 (IL-2) has enabled clinical trials to test its in vivo effects. We report here the immunological effects of 7 consecutive days of IL-2 treatment given to 25 patients with cancer in a clinical Phase I study. Peripheral blood lymphocytes obtained from patients following therapy with IL-2 had(More)
T he complexity of modern engineered systems motivates the requirement for timely access to technical and operational documentation (Boy 1991, 1992). Documents are both the most valuable and the most expensive knowledge resource in engineering organizations (Carter 1992). Product and product-related documents may be intended for use by thousands of people(More)
In this paper we define the concept of conversation policies: declarative specifications that govern communications between software agents using an agent communication language. We discuss the role that conversation policies play in agent communication, and suggest several subtypes of conversation policy. Our reasoning suggests, contrary to current(More)