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Magnetic resonance is an exceptionally powerful and versatile measurement technique. The basic structure of a magnetic resonance experiment has remained largely unchanged for almost 50 years, being mainly restricted to the qualitative probing of only a limited set of the properties that can in principle be accessed by this technique. Here we introduce an(More)
PURPOSE To evaluate an augmented reality (AR) system in combination with a 1.5-T closed-bore magnetic resonance (MR) imager as a navigation tool for needle biopsies. MATERIALS AND METHODS The experimental protocol had institutional animal care and use committee approval. Seventy biopsies were performed in phantoms by using 20 tube targets, each with a(More)
In this study, we registered live-time interventional magnetic resonance imaging (iMRI) slices with a previously obtained high-resolution MRI volume that in turn can be registered with a variety of functional images, e.g., PET, SPECT, for tumor targeting. We created and evaluated a slice-to-volume (SV) registration algorithm with special features for its(More)
We evaluated semiautomatic, voxel-based registration methods for a new application, the assessment and optimization of interventional magnetic resonance imaging (I-MRI) guided thermal ablation of liver cancer. The abdominal images acquired on a low-field-strength, open I-MRI system contain noise, motion artifacts, and tissue deformation. Dissimilar images(More)
Echo shifted (ES) gradient-recalled echo sequences (whose TE > TR) have found important applications in fMRI and MR thermometry since their introduction. The technique increases T *(2) weighting in BOLD imaging and temperature change sensitivity in phase-based temperature imaging compared to FLASH sequences. Yet, inconsistent observations have previously(More)
We are investigating interventional MRI (iMRI) guided thermal ablation treatment of the prostate cancer. Functional images such as SPECT can detect and localize tumor in the prostate not reliably seen in MRI. We intend to combine the advantages of SPECT with iMRI-guided treatments. Our concept is to first register the low-resolution SPECT with a high(More)
PURPOSE To determine whether consistent regions of activity could be observed in the lumbar spinal cord of single subjects with spin-echo functional MRI (fMRI) if several repeated experiments were performed within a single imaging session. MATERIALS AND METHODS Repeated fMRI experiments of the human lumbar spinal cord were performed at 1.5 T with a(More)
The goal of this research is to register real-time interventional magnetic resonance imaging (iMRI) slice images with a previously obtained high-resolution MRI image volume, which in turn can be registered with functional images such as those from SPECT. The immediate application is in iMRI-guided treatment of prostate cancer, where additional images are(More)