Jeffrey J. Lohmiller

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Obese (n = 8) and nonobese (n = 6) adult rhesus monkeys (Macaca mulatta) were assessed in terms of body size and distribution of body fat, glucose tolerance, and serum lipid, insulin, and androgen levels. The weights of the obese monkeys were more than 2 SD above the mean for their sex, while the nonobese monkeys averaged less than 0.25 SD from the mean.(More)
Helicobacter pullorum is a bacterial pathogen in humans. By using microaerobic culture techniques, H. pullorum was isolated from the feces of barrier-maintained mice and identified, on the basis of biochemical, restriction fragment length polymorphism, and 16S rRNA gene sequence analyses. This finding presents an opportunity to study H. pullorum(More)
Diseases of bulbourethral glands have rarely been reported in mice. The present report describes bulbourethral gland cysts in three male mice: a.1yearold DBA/2J mouse (case 1), a 10monthold nude mouse (case 2), and a 4.5monthold chimeric mouse (case 3). Round to oval fluctuant nodules were observed on their dorsal perineum. The nodules in cases 1 and 2 were(More)
A case of epidermotropic lymphoma with systemic spread into lymph nodes and visceral organs was observed in a 7- to 8-month-old, female ICR mouse. The mouse developed progressive and generalized alopecia and lymphadenopathy of several weeks' duration. The affected skin was markedly and diffusely thickened, with multiple serous to hemorrhagic crusts,(More)
Crystals were detected in glass bottles containing autoclaved (standard cycle: 1218 C, 17 lb/in2, for 20 min) tap water. Bottles were fitted with a sipper tube and stopper. Crystals were observed twice at approximately a 6-month interval. Analysis of crystals and crystal-laden water by transmission electron microscopy and inductively coupled plasma and(More)
Glutathione (GSH) is the most important cytosolic antioxidant. Since GSH levels are decreased with age, we hypothesized that T-lymphocytes from old mice would be more sensitive to oxidative stress. T-lymphocytes from young and old mice were exposed to hypoxanthine/xanthine oxidase, and lymphocyte viability, proliferation, GSH content, and calcium signaling(More)
This article is written to provide differential diagnostic help for the practitioner who suspects respiratory disease in rodents or rabbits. The authors are laboratory animal veterinarians who work with rodents and rabbits on a herd health basis but also have considerable experience dealing with individual mice, rats, guinea pigs, hamsters, gerbils, and(More)
Many people who work in laboratory rodent breeding facilities believe that disrupting certain sensitive rodent lines will result in increased breeding failures and loss of newborn pups. To evaluate this hypothesis, the authors assessed the effect of cage-change frequency on the breeding performances of a mouse strain (C57BL/6NTac) and a rat stock(More)
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