Jeffrey Godwin

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The association between occupational and other environmental exposures was evaluated in 60 acute myelogenous leukemia cases and controls. Odds ratios and 95% confidence intervals for prior cytotoxic therapy and benzene exposure, adjusted for age, sex, and race by logistic regression, were 3.7 (0.7, 19.9) and 2.6 (0.4, 15.2), respectively. No other(More)
A 67-year-old man developed hepatic and renal failure over a six-day period. Despite full supportive measures, he died on his 11th day of hospitalization with fulminant DIC and hepatic, renal, and respiratory failure. Postmortem examination revealed acid-fast bacilli in virtually all organ systems. Miliary tuberculosis should be considered as a potentially(More)
The tracheotomized patient undergoing mechanical ventilation presents numerous challenges to the intensive care team. During the initial phase of respiratory failure, patient instability and risks of multiorgan failure focus efforts on an array of critical care management techniques designed to reverse the underlying process and prevent complications.(More)
Takayasu's arteritis (TA) is a rare, chronic, and idiopathic vasculitis of the aorta and/or its main branches. There have been case reports of this disease associated with immune hypercoaguable states, namely raised antiphospholipid antibodies. Investigations of the thrombotic nature of Takayasu's arteritis have shown elevated levels of B-thromboglobulin,(More)
OBJECTIVE To compare the dosing requirements and international normalized ratios (INRs) associated with two bioequivalent crystalline warfarin sodium products in patients with chronic atrial fibrillation. METHODS A multicenter, single-blind (prescriber), randomized, crossover evaluation of Apothecon warfarin and DuPont warfarin (Coumadin) was conducted in(More)
Previous studies have shown that washed human platelets attenuate oxidant oedema in isolated perfused rabbit lungs through mechanisms dependent on platelet glutathione. We hypothesized that the platelet glutathione redox cycle scavenges hydrogen peroxide in this model and thereby protects vascular endothelial cells from oxidant injury. This hypothesis was(More)
A 26-year-old man developed progressive weakness over a two-month period. His chest radiograph showed diffuse interstitial infiltrates, and transbronchial lung biopsies demonstrated noncaseating granulomas consistent with sarcoidosis. Sarcoid neuropathy should be considered in the differential diagnosis of the patient presenting with an atypical(More)