Jeffrey Fisher

Benjamin Blount2
Mark E Wilson2
2Benjamin Blount
2Mark E Wilson
Learn More
Chronic stress can have a deleterious effect on the re-productive axis that, for females, is manifested in an increased incidence of infertility. However, gonadal steroids may, in turn, affect a female's response to stress as measured by activity within the limbic-hypothalamic-pituitary-adrenal (LHPA) axis. What is not clear is whether a history of exposure(More)
Entity resolution (ER) is a common data cleaning task that involves determining which records from one or more data sets refer to the same real-world entities. Because a pairwise comparison of all records scales quadratically with the number of records in the data sets to be matched, it is common to use blocking or indexing techniques to reduce the number(More)
Post-exposure risk assessment of chemical and environmental stressors is a public health challenge. Linking exposure to health outcomes is a 4-step process: exposure assessment, hazard identification, dose response assessment, and risk characterization. This process is increasingly adopting "in silico" tools such as physiologically based pharmacokinetic(More)
Physiologically Based Pharmacokinetic (PBPK) models can be used to determine the internal dose and strengthen exposure assessment. Many PBPK models are available, but they are not easily accessible for field use. The Agency for Toxic Substances and Disease Registry (ATSDR) has conducted translational research to develop a human PBPK model toolkit by(More)
BACKGROUND Population-based and longitudinal information regarding sexual risk behavior among patients with multidrug resistant (MDR) HIV and their sexual partners is of great public health and clinical importance. OBJECTIVE To characterize the HIV sexual risk behaviors of patients with and without drug-resistant HIV in the clinical care setting over(More)
Textual databases are ubiquitous in many application domains. Examples of textual data range from names and addresses of customers to social media posts and bibliographic records. With online services, individuals are increasingly required to enter their personal details for example when purchasing products online or registering for government services,(More)
Potassium iodide (KI) is recommended as an emergency treatment for exposure to radioiodines, most commonly associated with nuclear detonation or mishaps at nuclear power plants. Protecting the thyroid gland of infants and children remains a priority because of increased incidence of thyroid cancer in the young exposed to radioiodines (such as (131)I and(More)
Radioactive iodide ((131)I-) protection studies have focused primarily on the thyroid gland and disturbances in the hypothalamic-pituitary-thyroid axis. The objective of the current study was to establish (131)I- urinary excretion profiles for saline, and the thyroid protectants, potassium iodide (KI) and ammonium perchlorate over a 75 hour time-course.(More)