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BACKGROUND Sinonasal lymphoma is a rare rhinologic entity. We present a case series and review the literature surrounding the diagnosis and management of this disease. METHODS A pathology database spanning 22 years at a tertiary care center was searched for a diagnosis of lymphoma in the paranasal sinuses or the nasal cavity. Seventeen cases were(More)
OBJECTIVE To determine the incidence and causes of perioperative complications in patients who undergo microvascular free flap procedures for reconstruction of the head and neck. SETTING Academic tertiary care medical center. PATIENTS AND METHODS A total of 400 consecutive microvascular free flap procedures were performed for reconstruction of the head(More)
PURPOSE The purpose of this study was to determine whether a liposomal formulation of curcumin would suppress the growth of head and neck squamous cell carcinoma (HNSCC) cell lines CAL27 and UM-SCC1 in vitro and in vivo. EXPERIMENTAL DESIGN HNSCC cell lines were treated with liposomal curcumin at different doses and assayed for in vitro growth suppression(More)
Previous experiments have shown that curcumin or cisplatin treatment suppresses growth of head and neck squamous cell carcinoma (HNSCC). To study the potential cooperative effect of both agents, two HNSCC cell lines were treated with curcumin or cisplatin alone or in combination. In vivo studies consisted of intravenous tail vein injection of liposomal(More)
OBJECTIVE To determine factors predicting the outcome after salvage surgery with microvascular flap reconstruction for recurrent squamous cell cancer (SCC) of the head and neck. STUDY DESIGN This is a retrospective analysis of patients treated at an academic medical center. METHODS One hundred six patients underwent salvage surgery and microvascular(More)
BACKGROUND The Keros classification scheme has been used to describe the ethmoid skull-base configuration; however, this scheme only partially addresses key anatomic issues in ethmoid skull-base injury avoidance during surgery. METHODS Coronal computed tomography (CT) scans were reviewed for 200 patients undergoing sinus evaluation at a tertiary care(More)
BACKGROUND Pleomorphic adenoma (PA) is the most common benign neoplasm of the major salivary glands. PA of the paranasal sinuses and skull base is an extremely rare pathologic entity. We report 3 cases of sinonasal and skull-base PA (including locoregionally advanced parotid disease) and review other cases in the literature, with special attention to(More)
BACKGROUND Transnasal approaches to the anterolateral maxillary sinus and infratemporal fossa are challenging with traditional endoscopic techniques and instrumentation. Additional access in the anterior and lateral direction can be obtained with modified endoscopic medial maxillectomy (MEMM) or total endoscopic medial maxillectomy (TEMM) or via a(More)
OBJECTIVE Our objective was to determine which factors are associated with cancer recurrence after microvascular reconstruction of the head and neck for squamous cell carcinoma (SCC). STUDY DESIGN A cohort of patients who fit the inclusion/exclusion criteria were identified retrospectively. METHODS A group of 184 patients who underwent successful(More)
OBJECTIVE To evaluate the outcome and complications of reirradiation of recurrent head and neck cancer after salvage surgery and microvascular reconstruction. STUDY DESIGN Retrospective. SUBJECTS AND METHODS Twelve patients underwent salvage surgery with microvascular reconstruction for recurrent or second primary head and neck cancer in a previously(More)