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Hippocampal synaptic plasticity and learning are strongly regulated by metabotropic glutamate receptors (mGluRs) and particularly by mGluR5. Here, we investigated the mechanisms underlying mGluR5-modulation of these phenomena. Prolonged pharmacological blockade of mGluR5 with MPEP produced a profound impairment of spatial memory. Effects were associated(More)
Simulium metallicum sibling species E was identified cytotaxonomically from an onchocerciasis focus at Altamira in northern Venezuela. S. metallicum E larvae were sampled monthly from two small mountain streams over a 15-month period (July 1990 to September 1991) and eleven habitat variables were measured at two altitudes. One stream consistently harboured(More)
The larval polytene chromosomes of Anopheles triannulatus are described for the first time in this report. The population from western Venezuela was chosen arbitrarily as the chromosome standard and is the basis for the photomap presented here. Anopheles trannulatus displays whole-arm associations distinct from other members of the subgenus Nyssorhynchus(More)
  • J Conn
  • 1990
A photomap of larval polytene chromosomes of Anopheles nuneztovari (population B) from western Venezuela is presented. Samples of An. nuneztovari B taken from 4 study sites in the states of Barinas and Táchira comprise a single panmictic population, which is chromosomally identical to the cytotype identified by Kitzmiller et al. (1973) from western(More)
Polytene chromosome studies were undertaken to elucidate taxonomic relationships among populations of Anopheles aquasalis and A. emilianus in Venezuela. Four collection sites were chosen: two in Sucre state (Santa Fe and Guayana) where A. aquasalis (considered to be A. emilianus by Gabaldón and Escalante) is presumed to be the major regional vector of(More)
The English spoken in the Pacific Northwestern United States (PNWE) has received minimal research attention in variationist sociolinguistics. Labov, Ash and Boberg (2006) and Wolfram and Schilling-Estes (1996) describe this comparatively new region of the United States as likely to show widespread phonological variation due to dialect contact-consistent(More)