Jeffrey A. Townsend

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An efficient method for making directed DNA sequence modifications to plant genes (gene targeting) is at present lacking, thereby frustrating efforts to dissect plant gene function and engineer crop plants that better meet the world's burgeoning need for food, fibre and fuel. Zinc-finger nucleases (ZFNs)-enzymes engineered to create DNA double-strand breaks(More)
[1] This paper summarizes Spirit Rover operations in the Columbia Hills, Gusev crater, from sol 1410 (start of the third winter campaign) to sol 2169 (when extrication attempts from Troy stopped to winterize the vehicle) and provides an overview of key scientific results. The third winter campaign took advantage of parking on the northern slope of Home(More)
In the version of this correspondence initially published, the two previously published datasets analyzed were labeled with incorrect references in Figure 1b. Reference 2 should be associated with the second column (80 sites), and reference 3 should be associated with the third column (96 sites). In the " Battle of the chips " section, the Infinium assay(More)
Cerebrotendinous xanthomatosis is a familial recessive disorder. Patients with the disorder present with tendon xanthomas, juvenile cataracts, dementia, and pyramidal and cerebellar abnormalities but have normal plasma cholesterol. High plasma cholestanol concentrations and abnormal bile acid metabolism are specific for this disease. The authors describe(More)
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