Jeffrey A. Magee

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The homeodomain-containing transcription factor NKX3.1 is a putative prostate tumor suppressor that is expressed in a largely prostate-specific and androgen-regulated manner. Loss of NKX3.1 protein expression is common in human prostate carcinomas and prostatic intraepithelial neoplasia (PIN) lesions and correlates with tumor progression. Disruption of the(More)
The IBM eServer௣ z990 microprocessor implements many features designed to give excellent performance on both newer and traditional mainframe applications. These features include a new superscalar instruction execution pipeline, high-bandwidth caches, a huge secondary translation-lookaside buffer (TLB), and an onboard cryptographic coprocessor. The(More)
As mainframes evolve and deliver higher performance, technologists are focusing less on processor speed and more on overall system performance to create optimized systems. One important area of focus for performance improvement involves chip-to-chip interconnects, with their associated bandwidths and latencies. IBM and related computer manufacturers are(More)
Many aspects of cellular physiology remain unstudied in somatic stem cells, for example, there are almost no data on protein synthesis in any somatic stem cell. Here we set out to compare protein synthesis in haematopoietic stem cells (HSCs) and restricted haematopoietic progenitors. We found that the amount of protein synthesized per hour in HSCs in vivo(More)
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