Jeff Wilkinson

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PURPOSE The development of a genetic signature for the identification of high-risk cutaneous melanoma tumors would provide a valuable prognostic tool with value for stage I and II patients who represent a remarkably heterogeneous group with a 3% to 55% chance of disease progression and death 5 years from diagnosis. EXPERIMENTAL DESIGN A prognostic 28-gene(More)
BACKGROUND A gene expression profile (GEP) test able to accurately identify risk of metastasis for patients with cutaneous melanoma has been clinically validated. OBJECTIVE We aimed for assessment of the prognostic accuracy of GEP and sentinel lymph node biopsy (SLNB) tests, independently and in combination, in a multicenter cohort of 217 patients. (More)
Patients with chronic hepatitis C frequently report tiredness, easy fatigability, and depression. The aim of this study is to determine whether hepatitis C virus (HCV) replication could be found in brain tissue in patients with hepatitis C and depression. We report two patients with recurrent hepatitis C after liver transplantation who also developed severe(More)
BACKGROUND The dynamics of hepatitis C virus (HCV) quasi species in the E2 region may correlate with the course of infection after orthotopic liver transplantation (OLT). METHODS Thirty-four patients who underwent transplantation for HCV-related cirrhosis were studied. Serum and liver samples were available before OLT and at 1 week, 4 months, and 1 year(More)
OBJECTIVE To describe rates of improved knowledge following a structured 2-day emergency obstetrics training course. METHODS Quantitative assessments to evaluate emergency obstetrics knowledge and practical skills were administered before, immediately after, and 3-9 months following the training course for 65 final-year medical students at the National(More)
PURPOSE Thymoma represents one of the rarest of all malignancies. Stage and completeness of resection have been used to ascertain postoperative therapeutic strategies albeit with limited prognostic accuracy. A molecular classifier would be useful to improve the assessment of metastatic behaviour and optimize patient management. METHODS qRT-PCR assay for(More)
UrbanSim is a game-based learning solution that is designed to train leaders in the execution of the " Art of Battle Command " in complex environments where counterinsurgency (COIN) and stability operations predominate. The UrbanSim experience is divided into three components: a two-hour, self-paced, instruction module that provides students with basic(More)
ii NOTICE The project that is the subject of this report was done under contract for the Virginia Department of Transportation, Virginia Transportation Research Council. The contents of this report reflect the views of the authors, who are responsible for the facts and the accuracy of the data presented herein. The contents do not necessarily reflect the(More)