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Recently, basic fibroblast growth factor (bFGF) has been found to increase trabecular bone mass and connectivity in the proximal tibial metaphyses (PTM) in osteopenic rats. The purpose of this study was to determine the bone anabolic effects of bFGF in the lumbar vertebral body (LVB), a less loaded skeletal site with a lower rate of bone turnover than the(More)
PURPOSE To quantify normal, in vivo tibio-femoral knee joint kinematics in multiple weight bearing positions using non-invasive, high-resolution MRI and discuss the potential of developing future kinematic methods to assess patients with abnormal joint pathologies. METHODS Ten volunteers with clinically normal knees pushed inferiorly on the footplate of a(More)
Five fresh cadaver pelves were cleaned of soft tissue and instrumented with strain gauges. The acetabula were reamed, and a cementless cup, oversized at the periphery, was inserted. The applied force and cup acceleration were measured during insertion and used to calculate an effective mass of the cup, insertion device, and pelvis during each impact.(More)
Overuse is thought to be the primary cause of chronic tendon injuries, in which forceful or repetitive loading results in an accumulation of micro-tears leading to a maladaptive repair response. In vitro organ culture models provide a useful method for examining how specific loading patterns affect the cellular response to load which may explain the early(More)
STUDY DESIGN In vivo investigation of intradiscal ultrasound thermal therapy in ovine cervical spine model. OBJECTIVE To evaluate the potential of interstitial ultrasound for selective heating of intradiscal tissue in vivo. SUMMARY OF BACKGROUND DATA Application of heat in the spine using resistive wire and radiofrequency current heating devices is(More)
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