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We investigated the radiographic and clinical course of 31 patients in whom a bulk acetabular allograft had been used during the cementless revision of a total hip replacement. Two patients died and two were lost to follow-up within 24 months, but of the remaining 27 acetabular components, 12 (44%) showed radiographic evidence of instability at a mean of 46(More)
A quantitative analysis of cortical bone remodeling was performed using calibrated videodensitometry. Six femoral specimens were obtained at autopsy from 3 patients treated with unilateral porous coated femoral components in situ > 6 years. Transverse thick sections of the remodeled and normal femora were obtained. Slab radiographs of the sections were(More)
Two acetabula which contained large bone allografts introduced at revision arthroplasty were obtained at post-mortem. The allografts had been placed in superior defects to support cementless acetabular components, and both hips were functioning well at the time of death. Clinical radiographs demonstrated apparent healing of graft to host bone, no graft(More)
Three proximally (40 per cent) and five extensively (80 per cent) porous-coated anatomic medullary locking femoral components were retrieved from seven cadavera at autopsy. Each component (with the surrounding, intact femur), was sectioned transversely at one-centimeter intervals. Backscattered scanning electron microscopy was used to evaluate(More)
Fifteen years of clinical experience with porous-coated prostheses demonstrated the durability of this type of fixation. This experience was documented by clinical follow-up study of the 393 cases treated by the senior author before 1985. Only six of these femoral components have been revised: three for loosening, two for stem breakage, and one for(More)
Drosophila melanogaster has proven to be a useful model system for the genetic analysis of ethanol-associated behaviors. However, past studies have focused on the response of the adult fly to large, and often sedating, doses of ethanol. The pharmacological effects of low and moderate quantities of ethanol have remained understudied. In this study, we tested(More)
Using Drosophila melanogaster larvae we asked whether distinct aversive stimuli have a common neural representation during associative learning. We tested the interchangeability of heat shock and electroshock punishments when used within a single olfactory associative conditioning experiment. We find that compared to animals trained with the repetitive use(More)
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