Jeff Barrick

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The common loss region on the short arm of chromosome 3 (3p) in human breast tumors harbors two members of the c-erbA receptor gene family, c-erbA2 and c-erbA-beta, both of which recognize a BamHI polymorphism in human genomic DNA. Analysis of lymphocyte DNAs from 50 normal individuals and lymphocyte DNAs from 50 normal individuals and lymphocyte and tumor(More)
In vitro selection has proven itself as a great tool for isolating functional single stranded RNA sequences from large random pools. However, the multitude of available folding pathways leave many potentially functional sequences in misfolded states. This research aimed to use kinetic folding simulations of single-stranded RNA to test thermocycling as a(More)
Somatic cell hybrids between either normal human fibroblasts, phenotypically normal mouse fibroblasts or mouse peritoneal macrophages and HT1080 human diploid fibrosarcoma cells were studied for their ability to form tumors in nude mice. The results of this study indicate that tumorigenic behavior is expressed as a dominant trait in both human-human and(More)
In vitro selection has proven itself as a great tool for isolating functional single stranded RNA sequences from large random pools. However, the multitude of available folding pathways leave many potentially functional sequences in misfolded states. This research aimed to use kinetic folding simulations of single-stranded RNA to test thermocycling as a(More)
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