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While outcrop models can provide important information on reservoir architecture and heterogeneity, it is not entirely clear how such information can be used exhaustively in geostatistical reservoir modeling. Traditional, variogram-based geostatistics is inadequate in that regard since the variogram is too limiting in capturing geological heterogeneity from(More)
~Is paper was selected for presentation by an SPE Program Comm}ttee following review of information contained in an abstract ~ubmitted by the authors(s), Contents of the paper, n.. presented, have not been reviewed by the Society of Petroleum Engineers and are subject to cnmction by the author(s), Tbe material. as presented. dues not necessarily reflect any(More)
This paper was selected for presentation by an SPE Program Committee following review of information contained in an abstract submitted by the authors(s). Contents of the paper, as presented, have not been reviewd by the Society of Petroleum Engineers and are subject to correction by the author(s). The material, as presented, does not neccessarily reflect(More)
This paper was selected for presentation by an SPE Program Committee following review of information contained in an abstract submitted by the authors(s). Contents of the paper, as presented, have not been reviewd by the Society of Petroleum Engineers and are subject to correction by the author(s). The material, as presented, does not neccessarily reflect(More)
Two geostatistical methods for history matching are presented. Both rely on the sequential simulation principle for generating geologically sound realizations. The first method relies on perturbing the sequential simulation through the perturbation of the conditional distribution models; the second method relies on the perturbation of random numbers. We(More)
Aplidin is an antitumour drug, currently undergoing phase II evaluation in different haematological and solid tumours. In this study, we analysed the antimyeloma effects of Aplidin in the syngeneic 5T33MM model, which is representable for the human disease. In vitro, Aplidin inhibited 5T33MMvv DNA synthesis with an IC(50) of 3.87 nM. On cell-cycle(More)