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PROBLEM To determine whether the ACE D/D genotype or the combination of PAI-1 4G/4G and ACE D/D genotypes may serve as a risk factor for recurrent pregnancy loss. METHOD OF STUDY Buccal swabs were obtained from 120 women experiencing recurrent pregnancy loss and from 84 fertile control women. DNA was extracted from the buccal swab samples using the Qiagen(More)
PROBLEM We have previously reported the role of polymorphisms of thrombogenic genes involved in coagulation and fibrinolysis as risk factors for recurrent pregnancy loss. Thrombophilia has been viewed as a multigenic disorder rather than a monogenetic clinical phenotype and Apo E has been shown to play an important role in lipid metabolism in pregnancy. As(More)
OBJECTIVE The objective of our study was to determine how well CT predicts the need for laparotomy in hemodynamically stable patients with penetrating abdominal injury. MATERIALS AND METHODS We reviewed MEDLINE articles published from January 1994 through June 2008. The sensitivity, specificity, negative predictive value (NPV), positive predictive value(More)
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