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Anti-estrogen therapy has been shown to reduce mammographic breast density (MD). We hypothesized that a short-term change in breast density may be a surrogate biomarker predicting response to adjuvant endocrine therapy (ET) in breast cancer. We analyzed data for 1,065 estrogen receptor (ER)-positive breast cancer patients who underwent surgery between 2003(More)
BACKGROUND Our aim was to compare the accuracy of magnetic resonance imaging (MRI) and ultrasonography (US) in measuring the size of invasive breast cancer (IBC) and carcinoma in situ (CIS). We also examined the utility of routinely performing MRI in addition to US before breast-conserving surgery (BCS). PATIENTS AND METHODS Data from 1558 consecutive(More)
OBJECTIVES The present study tried to identify factors predictive of upstaging from ultrasound-guided core needle biopsy (CNB)-diagnosed ductal carcinoma in situ (DCIS) to invasive cancer after surgical excision. MATERIALS AND METHODS We enrolled 506 female CNB-diagnosed DCIS patients who underwent subsequent surgical excision between January 2000 and(More)
After publication of their article [1], the authors noted an error under the section " Density change and recurrence-free survival ". Where it currently reads " After adjusting for confounding factors, patients with MDRR ≥ 15% had a higher risk of recurrence than patients with MDRR <15% (HR 1.60, 95% CI 1.02 to 2.50, P = 0.041) (Additional fi le 1, Table(More)
PURPOSE The need for surgical excision in patients with ultrasound-guided core needle biopsy (CNB)-diagnosed atypical ductal hyperplasia (ADH) remains an issue of debate. The present study sought to validate a scoring system (the U score, for underestimation) that we have previously developed for predicting malignancy in CNB-diagnosed ADH. METHODS The(More)
PURPOSE We evaluated the efficacy of breast magnetic resonance imaging (MRI) for detecting additional malignancies in breast cancer patients newly diagnosed by breast ultrasonography and mammography. METHODS We retrospectively reviewed the records of 1,038 breast cancer patients who underwent preoperative mammography, bilateral breast ultrasonography, and(More)
After publication of their article [1], the authors noted an error under the section " Density change and recurrence-free survival ". Where it currently reads " After adjusting for confounding factors, patients with MDRR ≥ 15% had a higher risk of recurrence than patients with MDRR <15% (HR 1.60, 95% CI 1.02 to 2.50, P = 0.041) (Additional fi le 1, Table(More)
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