The cerebral cortex needs to maintain information for long time periods while at the same time being capable of learning and adapting to changes. The degree of stability of physiological signals in the human brain in response to external stimuli over temporal scales spanning hours to days remains unclear. Here, we quantitatively assessed the stability… (More)
Epilepsy affects 50 million people worldwide, and seizures in 30% of the cases remain drug resistant. This has increased interest in responsive neurostimulation, which is most effective when administered during seizure onset. We propose a novel framework for seizure onset detection that involves (i) constructing statistics from multichannel intracranial EEG… (More)
Humans can recognize objects and scenes in a small fraction of a second. The cascade of signals underlying rapid recognition might be disrupted by temporally jittering different parts of complex objects. Here we investigated the time course over which shape information can be integrated to allow for recognition of complex objects. We presented fragments of… (More)
Visual recognition takes a small fraction of a second and relies on the cascade of signals along the ventral visual stream. Given the rapid path through multiple processing steps between photoreceptors and higher visual areas, information must progress from stage to stage very quickly. This rapid progression of information suggests that fine temporal… (More)
Episodic memories constitute the essence of our recollections and are formed by autobiographical experiences and contextual knowledge. Memories are rich and detailed, yet at the same time they can be malleable and inaccurate. The contents that end up being remembered are the result of filtering incoming sensory inputs in the context of previous knowledge.… (More)
Fisch et al. report in this issue of Neuron the results of an investigation of the neural correlates of conscious perception. They find an early, dramatic, and long-lasting gamma response in high-level visual areas, when (and only when) a rapidly presented image is perceived.
PURPOSE To describe for the first time in children the localization of sleep spindles, K-complexes, and vertex waves using subdural electrodes. METHODS We enrolled children who underwent presurgical evaluation of refractory epilepsy with subdural grid electrodes. We analyzed electroencephalogram data from subdural electrodes and simultaneous recording… (More)