To learn, obtain reward and survive, humans and other animals must monitor, approach and act on objects that are associated with variable or unknown rewards. However, the neuronal mechanisms that mediate behaviours aimed at uncertain objects are poorly understood. Here we demonstrate that a set of neurons in an internal-capsule bordering regions of the… (More)
Neurons in the primate dorsal striatum signal the uncertainty of object–reward associationsNeurons in the primate dorsal striatum signal the uncertainty of object–reward associations.
PURPOSE Computer-aided surgery is used in musculoskeletal tumor procedures to improve the surgeon's orientation to local anatomy during tumor resection. For the navigation system to function correctly, preoperative imaging (e.g., CT, MR) must be registered to the patient in the operating room. The goals of this study were (1) to directly quantify… (More)