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A weak antagonist of the pyrimidinergic receptor P2Y(14) containing a dihydropyridopyrimidine core was identified through high-throughput screening. Subsequent optimization led to potent, non-UTP… (More)
The parallel solution synthesis of three classes ofheterocycles is described. Arrays of pyridinethiones,pyridinones and thienopyridines were prepared usingone-step chemistry starting from readily… (More)