Jean-Yves Siriez

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Whether the high variable incubation period of cutaneous larva migrans depends on the parasite or other host factors remains unknown. Two brothers were contaminated simultaneously, but had 15- and 165-day incubation periods, respectively, suggesting a possible influence of host factors. A long incubation period does not rule out cutaneous larva migrans in(More)
We report on 4 patients (1 immunocompetent, 3 immunosuppressed) in whom visceral leishmaniasis had become unresponsive to (or had relapsed after) treatment with appropriate doses of liposomal amphotericin B. Under close follow-up, full courses of pentavalent antimony were administered without life-threatening adverse events and resulted in rapid and(More)
Febrile exanthema is a common symptom in returning travelers. In addition to cosmopolitan diseases, etiologies specific to the visited country must be considered. As an accurate diagnosis is important, clinical suspicion should be confirmed by laboratory tests. The case reports of three brothers returning from Indonesia highlight the possibility of(More)
Background Malaria infection among child travellers need special attention as it rarely occurs in non endemic countries. Most studies dealt with risks in the paediatric population, but there is a need to justify age class choices and its direct implication of analysis for severity risk factors. In this study we demonstrated that analysing the multi(More)
Post-malaria neurologic syndrome (PMNS) is a rare complication following a Plasmodium falciparum infection and its pathophysiology remains unclear. This is the first report of a pediatric PMNS following an infection acquired in Africa and the fourth description of pediatric PMNS overall. Neither intrathecal synthesis of IgG nor specific P. falciparum(More)
1 Service d’Accueil des Urgences Pédiatrique, Hôpital Robert-Debré-Assistance Publique-Hôpitaux de Paris, Paris, France, 2 Laboratoire de Parasitologie et de Mycologie, Hôpital Pitié-Salpêtrière-Assistance Publique-Hôpitaux de Paris, Paris, France, 3 Service des Maladies Infectieuses et Tropicales, Hôpital Tenon-Assistance Publique-Hôpitaux de Paris, Paris,(More)
In order to assess cardiac tolerance of halofantrine in children, we studied, retrospectively, 15 non complicated falciparum malaria cases treated with halofantrine, and focused on the effect on ventricular repolarisation. Our data showed that halofantrine can produce a moderate QTc prolongation without any life-threatening arrhythmia. As long as(More)
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