Jean-Sebastien Hoffmann

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(2009) Lipophilic prodrugs of amino acids and vitamin E as osmolytes for the compensation of hyperosmotic stress in human keratinocytes. The function of the Na+-driven flagellum of Vibrio cholerae is determined by osmolality and pH. Brutschy B (2010) ATP synthases: cellular nanomotors characterized by LILBID mass spectrometry. (2011) Draft genome sequence(More)
The unusually high frequency of misincorporation by HIV-1 reverse transcriptase (HIV RT) is likely to be the major factor in the rapid accumulation of viral mutations in AIDS, especially in the env gene. To investigate the ability of HIV RT to copy the env gene, we subcloned an HIV env gene fragment into a single-stranded DNA vector and measured the(More)
The physiological function of the human DNA polymerase θ (pol θ) is still unclear despite its in vitro translesion synthesis capacity during DNA damage repair process. However this DNA polymerase is always present along the cell cycle in the absence of replication stress and DNA damage. Is there a different molecular function? We present the genomic data of(More)
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