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OBJECTIVE To develop a model to assess severity of illness and predict vital status at hospital discharge based on ICU admission data. DESIGN Prospective multicentre, multinational cohort study. PATIENTS AND SETTING A total of 16,784 patients consecutively admitted to 303 intensive care units from 14 October to 15 December 2002. MEASUREMENTS AND(More)
OBJECTIVE To better define the incidence of sepsis and the characteristics of critically ill patients in European intensive care units. DESIGN Cohort, multiple-center, observational study. SETTING One hundred and ninety-eight intensive care units in 24 European countries. PATIENTS All new adult admissions to a participating intensive care unit between(More)
OBJECTIVES Acute renal failure is a complication in critically ill patients that has been associated with an excess risk of hospital mortality. Whether this reflects the severity of the disease or whether acute renal failure is an independent risk factor is unknown. The aim of this study was to analyze severity of illness and mortality in a group of(More)
Comprehension and satisfaction are relevant criteria for evaluating the effectiveness of information provided to family members of intensive care unit (ICU) patients. We performed a prospective randomized trial in 34 French ICUs to compare comprehension of diagnosis, prognosis, treatment, and satisfaction with information provided by ICU caregivers, in ICU(More)
OBJECTIVE Risk adjustment systems now in use were developed more than a decade ago and lack prognostic performance. Objective of the SAPS 3 study was to collect data about risk factors and outcomes in a heterogeneous cohort of intensive care unit (ICU) patients, in order to develop a new, improved model for risk adjustment. DESIGN Prospective multicentre,(More)
OBJECTIVE Patients with newly diagnosed cancer responsible for organ failures may require intensive care unit (ICU) admission and immediate chemotherapy. Outcomes in this population have not been studied. DESIGN Prospective observational cohort study. SETTING Teaching hospital. SUBJECTS All patients admitted to the ICU, from January 1997 to June 2003,(More)
Acute respiratory failure (ARF) in patients with cancer is frequently a fatal event. To identify factors associated with survival of cancer patients admitted to an intensive care unit (ICU) for ARF, we conducted a prospective 5-year observational study in a medical ICU in a teaching hospital in Paris, France. The patients were 203 cancer patients with ARF(More)
OBJECTIVE To evaluate risk factors in critically ill patients who were readmitted to an intensive care unit (ICU) during their hospital stay. DESIGN Prospective multicenter cohort study. PATIENTS AND SETTING A total of 15180 patients discharged from 30 medical, surgical and mixed ICUs in Austria over a 2-year period. MEASUREMENTS AND RESULTS The data(More)
OBJECTIVE To evaluate the opinions of intensive care unit staff and family members about family participation in decisions about patients in intensive care units in France, a country where the approach of physicians to patients and families has been described as paternalistic. DESIGN Prospective multiple-center survey of intensive care unit staff and(More)
INTRODUCTION The standardized mortality ratio (SMR) is commonly used for benchmarking intensive care units (ICUs). Available mortality prediction models are outdated and must be adapted to current populations of interest. The objective of this study was to improve the Simplified Acute Physiology Score (SAPS) II for mortality prediction in ICUs, thereby(More)