Jean-Pierre Ottoy

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Experimental results obtained in a batch reactor are presented showing different fast dynamic phenomena. All measured OUR-profiles show a 'start-up' phase upon substrate addition. Neither the response time of the DO-electrode, the mixing characteristics in the reactor or the extracellular transport limitations could explain this behaviour. It is(More)
Introduction Promotors and transcription factors regulate gene expression in eukaryotes. Eukaryotic transcription factors are highly modular proteins that activate or inhibit the transcription of genes by binding simultaneously to a recognition sequence element on the DNA and to the transcription machine. Gibbs sampling is a stochastic process that looks(More)
An intuitively appealing lack-of-fit test to assess the adequacy of a regression model is introduced together with a graphical diagnostic tool. The graphical method itself includes a formal testing procedure , and, it is particularly useful to detect the location of lack-of-fit. The procedure is based on regional residuals, using subsets of the space of the(More)
" Biosensors " are defined as sensors that allow the measurement and interpretation of the biological response of activated sludge to a known disturbance. The purpose of " biosensing " the activated sludge, on-line at the full-scale plant or off-line in lab-scale tests, is to obtain specific information about one or several activated sludge processes. This(More)
Classical approaches for analyzing reverse transcription quantitative polymerase chain reaction (RT-qPCR) data commonly require normalization before assessing differential expression (DE). Normalization often has a substantial effect on the interpretation and validity of the subsequent analysis steps, but at the same time it causes a reduction in variance(More)
Recently the authors have proposed tests for the one-sample and the k-sample problem, and a test for independence. All three tests are based on sample space partitions, but they were originally developed in different papers. Here we give an overview of the construction of these tests, stressing the common underlying concept of " sample space partitions. "
This project involves collecting didactic examples and datasets in the statistical field used for educational motives. Teachers often find it hard to come across good example datasets, accompanied with metadata of the collection procedure, the statistical methods used to analyze the data, which specific problems must be taken into account when conducting(More)
MOTIVATION Recently, De Neve et al. proposed a modification of the Wilcoxon-Mann-Whitney (WMW) test for assessing differential expression based on RT-qPCR data. Their test, referred to as the unified WMW (uWMW) test, incorporates a robust and intuitive normalization and quantifies the probability that the expression from one treatment group exceeds the(More)
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