Jean Pierre Leclerc

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BACKGROUND The aim of this study was to analyze SCLC patients beyond 30 months, particularly their outcome, their way of life, and factors which could influence relapses, second-primary cancers and death. PATIENTS AND METHODS Between January 1986 and May 1995, 263 SCLC patients who survived longer than 30 months were included from 52 French institutions.(More)
A new familial syndrome that affected 3 of 7 siblings is described. All 3 patients were young women with a very peculiar phenotype, poikilodermia and hair greying, and idiopathic nonarteriosclerotic cerebral calcifications. Pathological studies demonstrated a marked and progressive hyalinosis involving capillaries and often arterioles and small veins of the(More)
The diagnosis of heat exchangers on duty with respect to flow mal-distributions needs the development of non-intrusive inlet-outlet experimental techniques in order to perform an online fault diagnosis. Tracer experiments are an example of such techniques. They can be applied to mono-phase heat exchangers but also to multi-phase ones. In this case, the(More)
We report, to our knowledge, the first case of Trichosporon cutaneum endocarditis which developed in a 58-year-old woman 14 months after mitral valve replacement. The patient had not had antibiotic therapy. She was treated with an oral antifungal agent, ketoconazol, and prosthetic valve replacement. The initial outcome was favorable, but she died 5 months(More)
The distribution of A, B and H cell surface antigens was studied in 30 patients with bladder tumors using indirect immunofluorescence. These antigens, normally present at the surface of the healthy urothelium, disappear in various degrees in a large number of bladder tumors. Nevertheless, no close correlation exists between this loss of antigens, and the(More)