Jean-Marie Devoisselle

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Dendritic cells (DCs) are key cells in immunology that are able to stimulate or inhibit the immune response. RNA interference has appeared of great interest to modulate the expression of immunogenic or tolerogenic molecules. In our study, pH-sensitive polyion complex micelles based on a double-hydrophilic block copolymer and poly-L-lysine were formulated to(More)
Liposomes prepared from a mixture of L-alpha-dipalmitoylphosphatidylcholine and the PEGilated phospholipid N-(carbonylmethoxypoly(ethylene glycol 2000))-1,2-distearoyl-sn-glycero-3-phosphoethanolamine were used as templates for the production of silica and alkylated silica approximately 100 nm capsules, "liposils", entrapping aqueous solutions of anionic(More)
Purpose : To evaluate the in viva behavior of ICG and the evolution of ICG absorption and fluorescence properties after injection. Materials EL Methods : ICG (SERB, France) (15mglKg) was injected intravenously to 10 hamsters : 0 For 5 animals, fluorescence measurements were realized (Spectro-fluorimeter or Hamamatsu Argus 50 imaging system) on a vessel with(More)
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