Jean-Marc Guile

Learn More
OBJECTIVE To determine the baseline variables, including borderline personality disorder (BPD), associated with the six-month outcome of previously suicidal adolescents (n=263) presenting to an emergency department and treated predominantly as out-patients. METHODS Multivariate logistic regression was used to analyze the associations between baseline(More)
Duplications of chromosome 15 may be one of the most common single genetic causes of autism spectrum disorders (ASD), aside from fragile X. Most of the cases are associated with maternally derived interstitial duplication involving 15q11-13. This case report describes a female proband with a maternally derived interstitial duplication of proximal 15q. She(More)
BACKGROUND In a previous report, we hypothesized that responses to placebo were high in child and adolescent depression because of specific psychopathological factors associated with youth major depression. The purpose of this study was to compare the placebo response rates in pharmacological trials for major depressive disorder (MDD), obsessive compulsive(More)
1. Introduction Both clinicians and researchers are facing a huge increase in the prevalence of Pervasive Developmental Disorders (PDD) resulting in part from the expansion of the diagnostic criteria (Matson & Kozlowski, 2011). According to the DSM-IV-TR, the PDD group includes a wide variety of diverse conditions pertaining to the autism spectrum: The(More)
OBJECTIVE The aim of this study was to assess predictors of placebo response in all available short-term, placebo-controlled trials of psychotropic drugs for children and adolescents with internalizing disorders, major depressive disorder (MDD), obsessive compulsive disorder (OCD,) and anxiety disorders (ANX) exclusive of OCD and posttraumatic stress(More)
OBJECTIVE DSM-5 has added a new developmentally appropriate child and adolescent mood disorder subtype called disruptive mood dysregulation disorder (DMDD). The core features of DMDD are temper outbursts (manifested by either verbal rages and/or physical aggression) and unrelenting irritability or anger. Currently, the literature is lacking a thorough(More)
  • 1