Jean-Marc Ghigo

Publications133
h-index47
Citations7,901
Highly Influential Citations460
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Genetic analysis of Salmonella enteritidis biofilm formation: critical role of cellulose
We report here a new screening method based on the fluorescence of colonies on calcofluor agar plates to identify transposon insertion mutants of Salmonella enteritidis that are defective in biofilm… Expand
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BapA, a large secreted protein required for biofilm formation and host colonization of Salmonella enterica serovar Enteritidis
In environmental settings, biofilms represent the common way of life of microorganisms. Salmonella enterica serovar Enteritidis, the most frequent cause of gastroenteritis in developed countries,… Expand
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Global impact of mature biofilm lifestyle on Escherichia coli K‐12 gene expression
The formation of biofilm results in a major lifestyle switch that is thought to affect the expression of multiple genes and operons. We used DNA arrays to study the global effect of biofilm formation… Expand
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Candida albicans Biofilms: a Developmental State Associated With Specific and Stable Gene Expression Patterns
ABSTRACT Like many bacteria, yeast species can form biofilms on several surfaces. Candida albicans colonizes the surfaces of catheters, prostheses, and epithelia, forming biofilms that are extremely… Expand
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SarA and not σB is essential for biofilm development by Staphylococcus aureus
Staphylococcus aureus biofilm formation is associated with the production of the polysaccharide intercellular adhesin (PIA/PNAG), the product of the ica operon. The staphylococcal accessory… Expand
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CpxR/OmpR interplay regulates curli gene expression in response to osmolarity in Escherichia coli.
Curli fibers could be described as a virulence factor able to confer adherence properties to both abiotic and eukaryotic surfaces. The ability to adapt rapidly to changing environmental conditions… Expand
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Silent mischief: bacteriophage Mu insertions contaminate products of Escherichia coli random mutagenesis performed using suicidal transposon delivery plasmids mobilized by broad-host-range RP4…
Random transposon mutagenesis is the strategy of choice for associating a phenotype with its unknown genetic determinants. It is generally performed by mobilization of a conditionally replicating… Expand
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Natural conjugative plasmids induce bacterial biofilm development
Horizontal gene transfer is a principal source of evolution leading to change in the ecological character of bacterial species. Bacterial conjugation, which promotes the horizontal transfer of… Expand
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Definitions and guidelines for research on antibiotic persistence
Increasing concerns about the rising rates of antibiotic therapy failure and advances in single-cell analyses have inspired a surge of research into antibiotic persistence. Bacterial persister cells… Expand
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Antibiofilm polysaccharides.
Bacterial extracellular polysaccharides have been shown to mediate many of the cell-to-cell and cell-to-surface interactions that are required for the formation, cohesion and stabilization of… Expand
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