Jean-Luc Genet

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One of the major challenges facing the long term survival of neurons is their requirement to maintain efficient axonal transport over long distances. In humans as large, long-lived vertebrates, the machinery maintaining neuronal transport must remain efficient despite the slow accumulation of cell damage during aging. Mutations in genes encoding proteins(More)
Cymoxanil has been used for over 30 years to control grape downy mildew (Plasmopara viticola) in European vineyards, prevalently in mixture with other fungicides active on this disease. In the 1990’s cases of P. viticola resistant to cymoxanil were detected using a leaf disc assay. In this study, we establish that the presence of only 1 % of resistant(More)
  • Lu Watry, J Genet, Syndr Gene, Watry S, Lu J
  • 2013
As a group of G protein-coupled receptors (GPCRs) and ligand-gated ion channels (LGICs), the serotonin (5-HT) receptors are found in the central and peripheral nervous systems. After activated by the neurotransmitter serotonin, their natural ligand, 5-HT receptors mediate both excitatory and inhibitory neurotransmission by modulating the release of many(More)
  • J Genet Syndr, Gene Ther, Jayandharan And Srivastava, J Genet, Syndr Gene Ther, Gr Jayandharan +3 others
  • 2012
Introduction Blood clotting is a host defence mechanism that in parallel with the inflammatory responses helps not only protect the integrity of the vascular system but also promotes repair after tissue injury. This process involves a series of orderly steps involving components of the vasculature, platelets (primary hemostasis) and coagulation proteins(More)
box at the top right corner of the online article. Receive free email alerts when new articles cite this article. Sign up in the Notes articles must include the digital object identifier (DOIs) and date of initial publication. priority; they are indexed by PubMed from initial publication. Citations to Advance online prior to final publication). Advance(More)
(2008) Non-random error in genotype calling procedures: implications for family-based and case-control genome-wide association studies, Am (2008) Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci, (2008) Genome-wide association scan of quantitative traits for attention deficit hyperactivity disorder(More)
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