Jean Louis Pépin

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To investigate obstructive sleep apnea syndrome mechanisms, we developed a device to measure the surface electromyogram (EMG) time latency reflex of the genioglossus muscle stimulated by time and amplitude calibrated negative pharyngeal pressure drops. The reflex signals were found to be disturbed by transient signals that generate false alarms. Thus, to(More)
BACKGROUND Stable severe chronic obstructive pulmonary disease (COPD) patients with chronic hypercapnic respiratory failure treated by nocturnal bi-level positive pressure non-invasive ventilation (NIV) may experience severe morning deventilation dyspnea. We hypothesised that in these patients, progressive hyperinflation, resulting from inappropriate(More)
We have developed robust embedded algorithms for the real-time classification of activity detected by our wearable inertial device. We collected 224 h of accelerometric signals from 28 subjects [22 suffering from chronic obstructive pulmonary disease (COPD)] to develop and then evaluate our algorithms. We describe the process for determining the most robust(More)
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