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AIMS To evaluate by impression cytology (IC) the expression of the MHC class II inflammatory marker HLA-DR by the conjunctival epithelium, the cytological modifications of the conjunctival surface according to the Nelson's classification, and the eventual correlation between the two after severe ocular burns. METHODS A total of 24 patients (24 eyes) who(More)
BACKGROUND Identifying Crohn's disease recurrence in symptomatic patients after ileocaecal resection is difficult. The aim of this study was to evaluate faecal concentrations of granulocyte degradation products in this setting. METHODS A postoperative cohort of 13 patients was followed prospectively for 1 year with regular faecal calprotectin (FC) and(More)
PURPOSE To determine whether a combination of early amniotic membrane transplantation (AMT) and early topical corticosteroid treatment could be a safe adjuvant therapy during antibacterial treatment in severe bacterial keratitis (BK) for relieving pain, avoiding iatrogenic epithelial toxicity, and allowing earlier use of topical steroids. METHODS In a(More)
BACKGROUND/AIM To evaluate wavefront aberrations and subjective quality of life after toric intraocular lens (TIOL) implantation. METHODS Three groups of subjects who underwent unilateral cataract surgery with intraocular lens (IOL) implantation were compared: (1) toric group (n=40): corneal astigmatism >1.50 D, implanted with Acrysof toric SN60TT IOL(More)
CASE REPORT To report a rare case of optic neuropathy in refractory neurosarcoidosis treated with tumour necrosis factor-alpha antagonist (infliximab) perfusion. A 41-year-old man with diabetes presented with an abrupt, painless, unilateral visual loss. Thoracic computed tomography disclosed mediastinal lymphadenopathy, and evidence from histopathology(More)
PURPOSE To evaluate anterior segment modifications after penetrating keratoplasty (PKP), previous anterior chamber intraocular lens (IOL) removal, and Verisyse IOL (AMO) implantation over the iris or under the iris for the treatment of pseudophakic bullous keratopathy (PBK) using ultrasound biomicroscopy. SETTING Department of Ophthalmology, Poitiers(More)
INTRODUCTION The amniotic membrane (AM) is used for engineering ex vivo tissue constructs used in ocular surface reconstruction. Epidermal growth factor (EGF) content of the AM is believed to play a key role in supporting corneal epithelial cell expansion on AM. This study investigated EGF content in AM in relation to intra- and inter-donor variations and(More)
PURPOSE To present a new surgical technique combining penetrating keratoplasty and open-sky posterior iris fixation of the Artisan iris-claw intraocular lens (IOL) for treatment of pseudophakic bullous keratopathy in a case series of five patients. METHODS A graft diameter of 8.25 mm was chosen. The formerly implanted angle-supported IOL was removed. The(More)
PURPOSE To report a rare case of ocular localization of Cowden disease. DESIGN Case report. METHODS A 50-year-old woman with a history of multiple tumors was diagnosed with Cowden disease. A PTEN gene mutation was found. Visual acuity of the left eye had decreased 2 years before diagnosis. RESULTS Visual acuity was 20/20 in the right eye and 20/200 in(More)