Jean Golay

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Chick myelomonocytic cells transformed by the v-myb oncogene-containing viruses E26 and AMV differ in that the former resemble myeloblasts and express the v-myb-regulated granulocyte-specific mim-1 gene, while the latter resemble monoblasts and are mim-1 negative. We constructed a series of AMV-E26 chimeras and localized the critical differences between(More)
The v-myb, ets-containing avian leukemia virus E26 is unique in its capacity to transform both erythroblasts and myeloblasts. Previous studies showing that v-myb is sufficient for the transformation of myeloid cells failed to definitively establish the role of the v-ets gene. We have now isolated a mutant of E26, ts1.1, that is temperature-sensitive for(More)
The A-Myb transcription factor is structurally related to the c-myb proto-oncogene and is involved in the control of proliferation and/or differentiation of mature B lymphocytes. We have shown previously by PCR analysis that A-myb is preferentially expressed in CD38+ CD39- sIgM- mature B cells. We demonstrate here, using in situ hybridization, that A-myb(More)
A-myb is a member of the myb family of transcription factors, which regulates proliferation, differentiation, and apoptosis of hematopoietic cells. A-Myb expression is normally restricted to the proliferating B-cell centroblasts and transgenic mice overexpressing A-myb displayed enhanced hyperplasia of the lymph nodes. Because A-Myb is highly expressed in(More)
Data acquisition, storage and management have been improved, while the key factors of many phenomena are not well known. Consequently, irrelevant and redundant features artificially increase the size of datasets, which complicates learning tasks, such as regression. To address this problem, feature selection methods have been proposed. This research(More)
This paper deals with a new filter algorithm for selecting the smallest subset of features carrying all the information content of a data set (i.e. for removing redundant features). It is an advanced version of the fractal dimension reduction technique and it relies on the recently introduced Morisita esti-mator of Intrinsic Dimension (ID). Here, the ID is(More)
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