Jean-Georges Lorentz

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Brain-derived neurotrophic factor (BDNF) has been implicated in stimulating retinal ganglion cell (RGC) survival and axonal regeneration in rodent animal models in vivo and in vitro, but very little data are available on neurotrophin effects in higher mammals. We hence analysed BDNF signalling in primary cultures of adult pig RGC. As detected by(More)
The effect of maternal alcohol consumption during pregnancy and lactation on gamma-aminobutyric acid (GABA) levels in different rat brain regions of 3-week-old pups was investigated. There was a significant decrease in the thalamus, pons, cerebellum and hippocampus, no change in posterior colliculus, occipital cortex, temporal cortex, hypothalamus, septum(More)
In the European hamster, Cricetus cricetus, a common hibernator, over a year, the gamma-aminobutyric acid (GABA) content has been followed, in the cytosolic and crude synaptosomal fractions of the olfactory bulbs, hypothalamus and cerebellum. In these 3 areas, the GABA content shows circannual variations of endogenous origin: in this period, in both(More)
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