Jean-François Vibert

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BACKGROUND Present guidelines recommend routine daily chest radiographs for mechanically ventilated patients in intensive care units. However, some units use an on-demand strategy, in which chest radiographs are done only if warranted by the patient's clinical status. By comparison between routine and on-demand strategies, we aimed to establish which(More)
It is still unclear whether the respiratory-like rhythm observed in slice preparations containing the pre-Bötzinger complex is of pacemaker or network origin. The rhythm persists in the absence of inhibition, but blocking pacemaker activity did not always result in rhythm abolition. We developed a computational model of the slice to show that(More)
There is experimental evidence that neuronal electrical activity directly influences neurite outgrowth during the development of the nervous system. Using model studies, Van Ooyen and Van Pelt extensively investigated the effect of this phenomenon upon network development and architecture. Their studies are based on the experimental observations that there(More)
A mathematical model is presented for the spread of viral diseases within human or other populations in which both the dynamics of viral growth within individuals and the interactions between individuals are taken into account. We thus bridge the classical macroscopic approach to the growth and population dynamics of disease at the microscopic level. Each(More)
BACKGROUND Interstitial lung diseases (ILDs) in children represent a heterogeneous group of rare respiratory disorders that affect the lung parenchyma. After the launch of the French Reference Centre for Rare Lung Diseases (RespiRare®), we created a national network and a web-linked database to collect data on pediatric ILD. METHODS Since 2008, the(More)
XNBC V9 is a software intended to simulate biological neural networks. Two types of neuron models are available: phenomenological, and ion-conductance based with several receptor types. Inputs to simulated neurons may come from experimental data stored in "les, to makèhybrida networks. Neurons and networks are described using graphic tools. Neurons can be(More)