Jean-François Gaudy

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The electroencephalogram (EEG), a highly complex signal, is one of the most common sources of information used to study brain function and neurological disorders. More than 100 current neural network applications dedicated to EEG processing are presented. Works are categorized according to their objective (sleep analysis, monitoring anesthesia depth,(More)
The effects of 33% nitrous oxide on the two components of the blink reflex were studied on seven healthy volunteers. The blink responses were elicited by a supraorbital nerve stimulation and recorded from the ipsilateral orbicularis oculi muscle. The intensity of stimulation was chosen at two to three times the reflex threshold in order to obtain stable(More)
The bronchodilator effects of ketamine were examined in human bronchial preparations contracted maximally with histamine, acetylcholine, barium chloride or potassium chloride. Antagonism between ketamine and either histamine or acetylcholine was examined also. Ketamine caused bronchial relaxation irrespective of the constricting agent, and exerted a partial(More)
The tidal volume-inspiratory duration relationship was studied during air breathing and rebreathing in conscious and anesthetized human subjects using three different intravenous agents. The results observed have been compared with similar experiments carried out in cats. Its has been shown that anesthesia provokes an increase in breathing rate associated(More)
The comparative effects of low doses (0.03-0.04 mg/kg) of epidural morphine on a nociceptive flexion reflex of the lower limb and on postoperative pain in volunteer patients were studied after orthopedic surgery on one knee. According to the stimulation parameters, it was found that 40-50 min after the injection, morphine produced an increase of 87% and 83%(More)
The search in man for experimental techniques suitable for study of the neurospecificity of anaesthetic drugs led us to use the blink reflex. Thirteen female volunteers undergoing gynaecological surgery received as a double-blind basis either 0.2 mg/kg of diazepam (7 cases) or 3 X 10(-1) mg/kg of fentanyl (6 cases) intravenously. The thresholds of the two(More)
Althesin was administered i.v. to eight dogs, using two different rates of infusion (6.55 +/- 2.13 microliter kg-1 min and 12.80 +/- 2.00 microliter kg-1 min). Ventilation (TI, TE, RR, TI/Ttot, VT, VE, VT/TI) and arterial blood-gas tensions were measured in air and during a 10-min period of 100% oxygen breathing. For both rates of Althesin infusion the(More)