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The structures of crystalline D-xylose isomerase (D-xylose ketol-isomerase; EC from Streptomyces rubiginosus and of its complexes with substrate and with an active-site-directed inhibitor(More)
The analogues of the coenzyme NADP+, nicotinamide--8-bromo-adenine dinucleotide phosphate (Nbr8ADP+) and 3-iodopyridine--adenine dinucleotide phosphate (io3PdADP+), were prepared. Nbr8ADP+ was found(More)
A new method of calculation, based on a direct fitting of the protein fluorescence intensity observed upon coenzyme binding (H.-P. Lutz, unpublished results), is used to study the negative(More)