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Finding better therapies for the treatment of brain tumors is hampered by the lack of consistently obtained molecular data in a large sample set and the ability to integrate biomedical data from disparate sources enabling translation of therapies from bench to bedside. Hence, a critical factor in the advancement of biomedical research and clinical(More)
Molecular diagnostic tools are increasingly being used in an attempt to classify primary human brain tumors more accurately. While methods that are based on the analysis of individual gene expression prove to be useful for diagnostic purposes, they are devoid of biological significance since tumorgenesis is a concerted deregulation of multiple pathways(More)
BACKGROUND Genomic copy number alterations are widely associated with a broad range of human tumors and offer the potential to be used as a diagnostic tool. Especially in the emerging era of personalized medicine medical informatics tools that allow the fast visualization and analysis of genomic alterations of a patient's genomic profile for diagnostic and(More)
• Analyzed high-throughput genomic, genetic, and epigenetic data sets in glioma. • Developed a tool for reverse engineering gene regulatory networks via parallel programming. • Involved in developing a web-based tool for assigning glioma patients to specific molecular subtypes. • Involved in developing a web-based tool for reporting copy number alterations(More)
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