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  • Jean Bou, Teresa Huélamo Doménech, +5 authors Jose Maria Palacios
  • Chemistry, Medicine
  • European journal of pharmacology
  • 2000 (First Published: 1 December 2000)
  • Almotriptan (3-[2-(dimethylamino)ethyl]-5-(pyrrolidin-1-ylsulfonylmethyl )-1H-indo le) has been studied in several models predictive of activity and selectivity at 5-HT receptors. Almotriptan showedContinue Reading
  • Jean Bou, Jordi Riu Gras, Julio Cortijo, Esteban Jesús Morcillo, J. Sole Llenas, Jose Maria Palacios
  • Medicine
  • Cephalalgia : an international journal of…
  • 2001 (First Published: 1 October 2001)
  • This paper describes the vascular effects of almotriptan in comparison with sumatriptan in human vessels and tissues in vitro. The contractile properties of almotriptan and sumatriptan were evaluatedContinue Reading
  • José Luis Martínez Ortíz, Julio Cortijo, José María Vallés, Jean Bou, Esteban Jesús Morcillo
  • Chemistry, Medicine
  • The Journal of pharmacy and pharmacology
  • 1993 (First Published: 1 December 1993)
  • Rolipram (0.1-1000 micrograms kg-1, i.v.) reduced the increase in microvascular permeability induced by platelet-activating factor (PAF; 50 ng kg-1, i.v.) at different sites of the guinea-pigContinue Reading