Jean Blancou

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The primary multiplication site of VVTGgRAB, a recombinant vaccinia virus (VV) expressing the rabies virus G glycoprotein, was studied in comparison with that of the parental VV Copenhagen strain, after oral administration to foxes. Foxes were fed with 10(8) TCID50 of either VVTGgRAB or VV and were sacrificed 12, 24, 48 or 96 h after inoculation. Both(More)
The pathogenicity of a vaccinia recombinant virus expressing the rabies glycoprotein (VVTGgRAB) was tested in several wild animal species which could compete with the natural rabies host, the red fox (Vulpes vulpes) in consuming vaccine baits in Europe. The following species were included in this study: wild boar (Sus scrofa), Eurasian badger (Meles meles),(More)
A total of 809 birds from Senegal, including 43 species and 21 families, were examined for hematozoans; 93 birds (11.5%) harbored blood parasites, with only 7 (7.5%) harboring mixed infections. Species of Haemoproteus occurred in 81.7% of the infected birds while species of Plasmodium. Trypanosoma, microfilaria and Leucocytozoon were encountered less(More)
SAG1, a rabies virus strain bearing one mutation which abolishes virulence for adult animals, was constructed from the SADBern strain of rabies virus which has previously been used as live vaccine for oral immunization of foxes. SAG1 also bears an antigenic mutation which serves as an additional marker of the strain. Studies on mice and four species of wild(More)
A total of 1650 birds of 56 species representing 21 families (primarily Passeriformes), was examined for blood parasites in the Lorraine region of France. Only 120 (7.3%) birds were infected, with members of the Paridae, Sylviidae and Turdidae the most frequently parasitized. Haemoproteids were the most commonly encountered parasites followed by the(More)
After a brief historical introduction, the authors describe a list of pathogens likely to be used by bioterrorists to adversely affect animal health and production, and eventually human health in case of zoonotic agents. The selection criteria for these numerous pathogens as well as the means available for their procurement, manipulation and dispersal are(More)
Thirty-three foxes (Vulpes vulpes) from a sample of 1912 collected in France were found to be infected with Trichinella spp. Four isolates were obtained for genetic identification. Isoenzymatic and biological analysis of these isolates revealed the presence of two distinct genetic types of Trichinella, Trichinella spiralis s.str. (T1) and Trichinella sp.(More)
From the many existing documents on the history of contagious bovine pleuropneumonia, it is possible to describe the practical measures adopted for disease surveillance and control from ancient times until the 19th century. Surveillance was based on diagnosis, post-mortem examination, animal inoculation and also on knowledge of the conditions under which(More)
We have investigated the influence of anti-rabies vaccination on the onset of the disease as well as the delay of death in foxes previously infected with rabies virus. A live vaccinia recombinant virus expressing the rabies virus glycoprotein (VVTGgRAB) was used as vaccine. Foxes were divided into six experimental groups of four animals. On day 0, each fox(More)